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GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility
To determine the function of germ cell nuclear factor (GCNF) in female reproduction, we generated an oocyte-specific GCNF knockout mouse model (GCNF(fl/fl)Zp3Cre(+)). These mice displayed hypofertility due to prolonged diestrus phase of the estrous cycle and aberrant steroidogenesis. These reproduct...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC175795/ https://ncbi.nlm.nih.gov/pubmed/12912906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg405 |
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