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Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export

The small GTPase Sar1p controls the assembly of the cytosolic COPII coat that mediates export from the endoplasmic reticulum (ER). Here we demonstrate that phospholipase D (PLD) activation is required to support COPII-mediated ER export. PLD activity by itself does not lead to the recruitment of COP...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Pathre, Purnima, Shome, Kuntala, Blumental-Perry, Anna, Bielli, Anna, Haney, Charles J., Alber, Sean, Watkins, Simon C., Romero, Guillermo, Aridor, Meir
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg390
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