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Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export

The small GTPase Sar1p controls the assembly of the cytosolic COPII coat that mediates export from the endoplasmic reticulum (ER). Here we demonstrate that phospholipase D (PLD) activation is required to support COPII-mediated ER export. PLD activity by itself does not lead to the recruitment of COP...

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Autori principali: Pathre, Purnima, Shome, Kuntala, Blumental-Perry, Anna, Bielli, Anna, Haney, Charles J., Alber, Sean, Watkins, Simon C., Romero, Guillermo, Aridor, Meir
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC175780/
https://ncbi.nlm.nih.gov/pubmed/12912905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg390
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