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A majority of fragile X males with methylated, full mutation alleles have significant levels of FMR1 messenger RNA
FMR1 mRNA levels were determined in peripheral blood leucocytes for 48 fragile X males with methylated, full mutation alleles that are resistant to cleavage by methylation sensitive enzymes. Using quantitative (fluorescence) RT-PCR, we observed that more than half of these males produce FMR1 mRNA, w...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMJ Group
2001
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1757182/ https://ncbi.nlm.nih.gov/pubmed/11432964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.38.7.453 |
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