One Lyn molecule is sufficient to initiate phosphorylation of aggregated high-affinity IgE receptors
In response to antigenic stimuli, the multisubunit immune recognition receptors become aggregated and then phosphorylated on their cytoplasmic tyrosines. For the clonotypic receptors of B and T cells and for Fc receptors such as the high-affinity receptor for IgE (FcɛRI), a Src family kinase initiat...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8615 |
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