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One Lyn molecule is sufficient to initiate phosphorylation of aggregated high-affinity IgE receptors

In response to antigenic stimuli, the multisubunit immune recognition receptors become aggregated and then phosphorylated on their cytoplasmic tyrosines. For the clonotypic receptors of B and T cells and for Fc receptors such as the high-affinity receptor for IgE (FcɛRI), a Src family kinase initiat...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Wofsy, Carla, Vonakis, Becky M., Metzger, Henry, Goldstein, Byron
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8615
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