Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: The IgG scaffold is important for induction and maintenance of immune hyporesponsiveness

IgG molecules can be highly tolerogenic carriers for associated antigens. Previously, we reported that recipients of bone marrow or lipopolysaccharide-stimulated B-cell blasts, both of which were retrovirally gene-transferred with an immunodominant peptide in-frame with the variable region of a muri...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kang, Yubin, Melo, Marco, Deng, Edward, Tisch, Roland, El-Amine, Moustapha, Scott, David W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8609
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