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Genetic association analysis of the IGFBP7, ADAMTS3, and IL8 genes as the potential osteoarthritis susceptibility that maps to chromosome 4q

Methods: Expression of IGFBP7, ADAMTS3, and IL8 in adult OA articular cartilage chondrocytes was demonstrated by reverse transcription-polymerase chain reaction. The genes were screened for common polymorphic DNA variants by direct sequencing of exons, intron-exon boundaries, and the 5' and 3&#...

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Bibliographic Details
Main Authors: Kawahara, C, Forster, T, Chapman, K, Carr, A, Loughlin, J
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1755421/
https://ncbi.nlm.nih.gov/pubmed/15708897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.027342
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