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DNA methylation is not likely to be responsible for aggrecan down regulation in aged or osteoarthritic cartilage
Objective: To investigate whether a correlation between gene methylation and expression of aggrecan in chondrocytes exists. Methods: The human aggrecan promoter region was analysed computationally for CpG-rich regions. These were investigated for the methylation of C residues in normal (aged) and os...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1755386/ https://ncbi.nlm.nih.gov/pubmed/15708898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2004.022509 |
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