Interleukin-12 (IL-12) and IL-18 synergistically induce the fungicidal activity of murine peritoneal exudate cells against Cryptococcus neoformans through production of gamma interferon by natural killer cells.

We examined the ability of interleukin-12 (IL-12) and IL-18 to induce the production of gamma interferon (IFN-gamma) and nitric oxide (NO) by murine peritoneal exudate cells (PEC) and to stimulate the growth-inhibitory activity of these cells against Cryptococcus neoformans. PEC produced IFN-gamma a...

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Publicado en:	Infect Immun
Autores principales:	Zhang, T, Kawakami, K, Qureshi, M H, Okamura, H, Kurimoto, M, Saito, A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.9.3594-3599.1997
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