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Interleukin-12 (IL-12) and IL-18 synergistically induce the fungicidal activity of murine peritoneal exudate cells against Cryptococcus neoformans through production of gamma interferon by natural killer cells.

We examined the ability of interleukin-12 (IL-12) and IL-18 to induce the production of gamma interferon (IFN-gamma) and nitric oxide (NO) by murine peritoneal exudate cells (PEC) and to stimulate the growth-inhibitory activity of these cells against Cryptococcus neoformans. PEC produced IFN-gamma a...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Zhang, T, Kawakami, K, Qureshi, M H, Okamura, H, Kurimoto, M, Saito, A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175511/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9284124/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.9.3594-3599.1997
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