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Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.

Secreted aspartyl proteinases (Saps), encoded by a gene family with at least nine members (SAP1 to SAP9), are one of the most discussed virulence factors produced by the human pathogen Candida albicans. In order to study the role of each Sap isoenzyme in pathogenicity, we have constructed strains wh...

詳細記述

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書誌詳細
主要な著者: Hube, B, Sanglard, D, Odds, F C, Hess, D, Monod, M, Schäfer, W, Brown, A J, Gow, N A
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC175503/
https://ncbi.nlm.nih.gov/pubmed/9284116
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