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Inhibition of leukotriene B(4)-induced CD11B/CD18 (Mac-1) expression by BIIL 284, a new long acting LTB(4) receptor antagonist, in patients with rheumatoid arthritis
Background: Leukotriene B4 (LTB(4)) has a key role in the pathophysiology of rheumatoid arthritis (RA). Objective: To investigate the inhibition of ex vivo LTB(4)-induced Mac-1 (CD11b/CD18) expression in leucocytes of patients with RA by the new oral LTB(4) receptor antagonist BIIL 284. Methods: The...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1754875/ https://ncbi.nlm.nih.gov/pubmed/14722206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2002.004499 |
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