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Interleukin (IL) 18 stimulates osteoclast formation through synovial T cells in rheumatoid arthritis: comparison with IL1ß and tumour necrosis factor α

Objective: To determine whether IL18 has any indirect effects on osteoclastogenesis mediated by T cells in RA synovium, and compare its effects with those of IL1ß and TNFα. Methods: Resting T cells were isolated from peripheral blood of healthy donors, and stimulated with 2 µg/ml phytohaemagglutinin...

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Autori principali: Dai, S, Nishioka, K, Yudoh, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754791/
https://ncbi.nlm.nih.gov/pubmed/15479886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.018481
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