A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen.

Several bacterial protein toxins require activation by eukaryotic proteases. Previous studies have shown that anthrax toxin protective antigen (PA), Pseudomonas exotoxin A (PE), and diphtheria toxin (DT) are cleaved by furin C-terminal to the sequences RKKR, RQPR, and RVRR, respectively. Because fur...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Gordon, V M, Rehemtulla, A, Leppla, S H
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC175476/
https://ncbi.nlm.nih.gov/pubmed/9234799
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki