Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene

Background: There is an association between C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene and methotrexate related toxicity. Objective: To examine the relations between the recently described A1298C polymorphism of the MTHFR gene, plasma homocysteine, methotrexate toxici...

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Detalhes bibliográficos
Main Authors: Berkun, Y, Levartovsky, D, Rubinow, A, Orbach, H, Aamar, S, Grenader, T, Abou, A, Mevorach, D, Friedman, G, Ben-Yehuda, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754756/
https://ncbi.nlm.nih.gov/pubmed/15361376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2003.016337
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