Sensitization of human umbilical vein endothelial cells to Shiga toxin: involvement of protein kinase C and NF-kappaB.

Infection of humans with Shiga toxin-producing Escherichia coli O157:H7 and Shigella dysenteriae 1 is strongly associated with vascular endothelial cell damage and the development of hemolytic-uremic syndrome. The cytotoxic effect of Shiga toxins on vascular endothelial cells in vitro is enhanced by...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Louise, C B, Tran, M C, Obrig, T G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.8.3337-3344.1997
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