Sensitization of human umbilical vein endothelial cells to Shiga toxin: involvement of protein kinase C and NF-kappaB.

Infection of humans with Shiga toxin-producing Escherichia coli O157:H7 and Shigella dysenteriae 1 is strongly associated with vascular endothelial cell damage and the development of hemolytic-uremic syndrome. The cytotoxic effect of Shiga toxins on vascular endothelial cells in vitro is enhanced by...

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Publié dans:	Infect Immun
Auteurs principaux:	Louise, C B, Tran, M C, Obrig, T G
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.8.3337-3344.1997
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