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Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies

Background: Sex hormones have been shown to influence the immune system and to modify the course of autoimmune disorders. Objective: To examine the effects of the oestrogen antagonist tamoxifen on the course of systemic lupus erythematosus (SLE) in (NZBxNZW)F1 mice. Methods: Groups of 8 week old (NZ...

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Detalhes bibliográficos
Main Authors: Sthoeger, Z, Zinger, H, Mozes, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754513/
https://ncbi.nlm.nih.gov/pubmed/12634234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.62.4.341
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