Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae antibody responses in mice.

Entamoeba histolytica is a significant cause of morbidity and mortality worldwide. The serine-rich E. histolytica protein (SREHP) is a surface-expressed trophozoite protein that includes multiple hydrophilic tandem repeats. A purified fusion protein between the dodecapeptide repeat of SREHP and chol...

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Autores principales: Ryan, E T, Butterton, J R, Zhang, T, Baker, M A, Stanley, S L, Calderwood, S B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC175440/
https://ncbi.nlm.nih.gov/pubmed/9234763
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