Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae antibody responses in mice.

Entamoeba histolytica is a significant cause of morbidity and mortality worldwide. The serine-rich E. histolytica protein (SREHP) is a surface-expressed trophozoite protein that includes multiple hydrophilic tandem repeats. A purified fusion protein between the dodecapeptide repeat of SREHP and chol...

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Pubblicato in:	Infect Immun
Autori principali:	Ryan, E T, Butterton, J R, Zhang, T, Baker, M A, Stanley, S L, Calderwood, S B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9234763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.8.3118-3125.1997
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