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Thrombin-induced expression of RANTES mRNA through protease activated receptor-1 in human synovial fibroblasts

Methods: A semiquantitative reverse transcriptase-polymerase chain reaction and reporter gene assay were performed using cultured human synovial fibroblasts from patients with RA. The up regulatory effects of thrombin on RANTES mRNA expression were tested. In addition, the roles of protease activate...

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Detalles Bibliográficos
Main Authors: Hirano, F, Kobayashi, A, Hirano, Y, Nomura, Y, Fukawa, E, Makino, I
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754231/
https://ncbi.nlm.nih.gov/pubmed/12176812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.61.9.834
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