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Total abrogation of collagen II-induced arthritis and the B cell response to type II collagen using suboptimal doses of a topoisomerase II antagonist

Objective: To assess the impact of etoposide, a topoisomerase II antagonist known to induce monocyte apoptosis, on the development of CIA. Methods: Mice were primed and booster immunised against collagen II (CII). One group of mice was treated with etoposide two days before CII immunisation and then...

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Detalhes bibliográficos
Main Authors: Verdrengh, M, Jonsson, I, Zaether, O, Bajtner, E, Holmdahl, R, Tarkowski, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1754218/
https://ncbi.nlm.nih.gov/pubmed/12176810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.61.9.829
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