Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice

INTRODUCTION: Dichloroacetate (DCA) has been in clinical use for the treatment of lactacidosis and inherited mitochondrial disorders. It has potent anti-tumor effects both in vivo and in vitro, facilitating apoptosis and inhibiting proliferation. The pro-apoptotic and anti-proliferative properties o...

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Main Authors: Bian, Li, Josefsson, Elisabet, Jonsson, Ing-Marie, Verdrengh, Margareta, Ohlsson, Claes, Bokarewa, Maria, Tarkowski, Andrej, Magnusson, Mattias
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787291/
https://ncbi.nlm.nih.gov/pubmed/19723321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2799
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