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Development of gene-switch transgenic mice that inducibly express transforming growth factor β1 in the epidermis

Previous attempts to establish transgenic mouse models to study the functions of transforming growth factor β1 (TGFβ1) in the skin revealed controversial roles for TGFβ1 in epidermal growth (inhibition vs. stimulation) and resulted in neonatal lethality in one instance. To establish a viable transge...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wang, Xiao-Jing, Liefer, Kristin M., Tsai, Sophia, O’Malley, Bert W., Roop, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8483
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