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Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes

The E6 and E7 oncoproteins of the high-risk human papillomavirus (HPV) types are able to immortalize human keratinocytes in vitro and likely contribute to the development of anogenital malignancies in vivo. The role of these oncoproteins in the productive viral life cycle, however, is not known. To...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Thomas, Jennifer T., Hubert, Walter G., Ruesch, Margaret N., Laimins, Laimonis A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8449
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