Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer

OBJECTIVE—To evaluate the influence of inactivation of one allele ("heterozygous knockout" or "heterozygous inactivation") of the type II procollagen gene (Col2a1) on the biomechanical properties and structure of the articular cartilage and subchondral bone in 15( )month old mice...

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Bibliografski detalji
Glavni autori: Hyttinen, M, Toyras, J, Lapvetelainen, T, Lindblom, J, Prockop, D, Li, S, Arita, M, Jurvelin, J, Helminen, H
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Extended Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753566/
https://ncbi.nlm.nih.gov/pubmed/11171689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.60.3.262
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