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A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation

The bacterial metabolism of short-chain aliphatic alkenes occurs via oxidation to epoxyalkanes followed by carboxylation to β-ketoacids. Epoxyalkane carboxylation requires four enzymes (components I–IV), NADPH, NAD(+), and a previously unidentified nucleophilic thiol. In the present work, coenzyme M...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Allen, Jeffrey R., Clark, Daniel D., Krum, Jonathan G., Ensign, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8432
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