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A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation

The bacterial metabolism of short-chain aliphatic alkenes occurs via oxidation to epoxyalkanes followed by carboxylation to β-ketoacids. Epoxyalkane carboxylation requires four enzymes (components I–IV), NADPH, NAD(+), and a previously unidentified nucleophilic thiol. In the present work, coenzyme M...

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Detalhes bibliográficos
Main Authors: Allen, Jeffrey R., Clark, Daniel D., Krum, Jonathan G., Ensign, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17533/
https://ncbi.nlm.nih.gov/pubmed/10411892
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