Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice.

The role of interleukin-6 (IL-6) in the pathogenesis of toxoplasmic encephalitis (TE) was examined by using IL-6-targeted mutant (IL-6(-/-)) mice. At 4 and 8 weeks after infection with the ME49 strain of Toxoplasma gondii, significantly greater numbers of T. gondii cysts and areas of inflammation as...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Suzuki, Y, Rani, S, Liesenfeld, O, Kojima, T, Lim, S, Nguyen, T A, Dalrymple, S A, Murray, R, Remington, J S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2339-2345.1997
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