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Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice.

The role of interleukin-6 (IL-6) in the pathogenesis of toxoplasmic encephalitis (TE) was examined by using IL-6-targeted mutant (IL-6(-/-)) mice. At 4 and 8 weeks after infection with the ME49 strain of Toxoplasma gondii, significantly greater numbers of T. gondii cysts and areas of inflammation as...

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Detalhes bibliográficos
Main Authors: Suzuki, Y, Rani, S, Liesenfeld, O, Kojima, T, Lim, S, Nguyen, T A, Dalrymple, S A, Murray, R, Remington, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175324/
https://ncbi.nlm.nih.gov/pubmed/9169772
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