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Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice.

The role of interleukin-6 (IL-6) in the pathogenesis of toxoplasmic encephalitis (TE) was examined by using IL-6-targeted mutant (IL-6(-/-)) mice. At 4 and 8 weeks after infection with the ME49 strain of Toxoplasma gondii, significantly greater numbers of T. gondii cysts and areas of inflammation as...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Suzuki, Y, Rani, S, Liesenfeld, O, Kojima, T, Lim, S, Nguyen, T A, Dalrymple, S A, Murray, R, Remington, J S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175324/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2339-2345.1997
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