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Urokinase-mediated fibrinolysis in the synovial fluid of rheumatoid arthritis patients may be affected by the inactivation of single chain urokinase type plasminogen activator by thrombin

BACKGROUND—Excessive fibrin deposition within the inflamed joints of rheumatoid arthritis (RA) patients suggests that local fibrinolysis is inefficient, which seems to be in contrast with the observed increased levels of urokinase type plasminogen activator (u-PA). Thrombin-mediated inactivation of...

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Bibliografiske detaljer
Main Authors: Braat, E, Jie, A, Ronday, H, Beekman, B, Rijken, D
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753115/
https://ncbi.nlm.nih.gov/pubmed/10733483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.4.315
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