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Urokinase-mediated fibrinolysis in the synovial fluid of rheumatoid arthritis patients may be affected by the inactivation of single chain urokinase type plasminogen activator by thrombin

BACKGROUND—Excessive fibrin deposition within the inflamed joints of rheumatoid arthritis (RA) patients suggests that local fibrinolysis is inefficient, which seems to be in contrast with the observed increased levels of urokinase type plasminogen activator (u-PA). Thrombin-mediated inactivation of...

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書誌詳細
主要な著者: Braat, E, Jie, A, Ronday, H, Beekman, B, Rijken, D
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1753115/
https://ncbi.nlm.nih.gov/pubmed/10733483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.4.315
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