Elevation of vacuolar pH inhibits the cytotoxic activity of furin-cleaved exotoxin A.
Exotoxin A (ETA) inhibits protein synthesis in cells by a process that involves receptor-mediated endocytosis and the transport of a 37-kDa proteolytic fragment across a membrane into the cytoplasm. The fragment is apparently generated by the endoprotease furin after the toxin has been endocytosed....
Na minha lista:
| Publicado no: | Infect Immun |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1997
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2240-2242.1997 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|