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Autocrine control of vitamin D metabolism in synovial cells from arthritic patients
OBJECTIVE—This study was designed to investigate whether 1,25-dihydroxyvitamin D(3) (1,25-(OH)(2)D(3)), produced by activated synovial fluid macrophages, promotes its own catabolism by upregulating vitamin D-24-hydroxylase (24-OHase) in synovial fibroblasts through a vitamin D receptor (VDR) mediate...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1752897/ https://ncbi.nlm.nih.gov/pubmed/10340962 |
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