Synthesis and immunological properties of Vi and di-O-acetyl pectin protein conjugates with adipic acid dihydrazide as the linker.

The Vi capsular polysaccharide of Salmonella typhi, a licensed vaccine for typhoid fever in individuals > or = 5 years old, induces low and short-lived antibodies in children, and reinjection does not elicit booster responses at any age. Its immunogenicity was improved by binding Vi to proteins by u...

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Pubblicato in:	Infect Immun
Autori principali:	Kossaczka, Z, Bystricky, S, Bryla, D A, Shiloach, J, Robbins, J B, Szu, S C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.6.2088-2093.1997
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