Synthesis of 6-PEtN-α-D-GalpNAc-(1–>6)-β-D-Galp-(1–>4)-β-D-GlcpNAc-(1–>3)-β-D-Galp-(1–>4)-β-D-Glcp, a Haemophilus influenzae lipopolysacharide structure, and biotin and protein conjugates thereof

Background: In bacteria with truncated lipopolysaccharide structures, i.e., lacking the O-antigen polysaccharide part, core structures are exposed to the immune system upon infection and thus their use as carbohydrate surface antigens in glycoconjugate vaccines can be considered and investigated. On...

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Hlavní autoři:	Andreas Sundgren, Martina Lahmann, Stefan Oscarson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Beilstein-Institut 2010-07-01
Edice:	Beilstein Journal of Organic Chemistry
Témata:	conjugate vaccines glycoconjugates Haemophilus influenzae lacto-N-neotetraose oligosaccharide synthesis thioglycosides
On-line přístup:	https://doi.org/10.3762/bjoc.6.80
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