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Synthesis of 6-PEtN-α-D-GalpNAc-(1–>6)-β-D-Galp-(1–>4)-β-D-GlcpNAc-(1–>3)-β-D-Galp-(1–>4)-β-D-Glcp, a Haemophilus influenzae lipopolysacharide structure, and biotin and protein conjugates thereof

Background: In bacteria with truncated lipopolysaccharide structures, i.e., lacking the O-antigen polysaccharide part, core structures are exposed to the immune system upon infection and thus their use as carbohydrate surface antigens in glycoconjugate vaccines can be considered and investigated. On...

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Autori principali: Andreas Sundgren, Martina Lahmann, Stefan Oscarson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2010-07-01
Serie:Beilstein Journal of Organic Chemistry
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Accesso online:https://doi.org/10.3762/bjoc.6.80
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