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Na(+)–K(+)–2Cl(−) cotransporter is implicated in gender differences in the response of the rat aorta to phenylephrine
1. Inhibition of the Na(+)–K(+)–2Cl(−) cotransporter (NKCC1) with bumetanide reduced contractile responses to phenylephrine (PE) in male rat aortas (129±4% of 60 mM KCl-induced contraction control vs 108±7% bumetanide; PE 10(−5) M; P<0.01) but did not change equivalent responses in female rat aor...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751927/ https://ncbi.nlm.nih.gov/pubmed/16799647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706818 |
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