The levosimendan metabolite OR-1896 elicits vasodilation by activating the K(ATP) and BK(Ca) channels in rat isolated arterioles

1. We characterized the vasoactive effects of OR-1896, the long-lived metabolite of the inodilator levosimendan, in coronary and skeletal muscle microvessels. 2. The effect of OR-1896 on isolated, pressurized (80 mmHg) rat coronary and gracilis muscle arteriole (∼150 μm) diameters was investigated b...

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Bibliografiset tiedot
Päätekijät: Erdei, Nóra, Papp, Zoltán, Pollesello, Piero, Édes, István, Bagi, Zsolt
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2006
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Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751872/
https://ncbi.nlm.nih.gov/pubmed/16715115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706781
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