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Blockade of HERG human K(+) channels and I(Kr) of guinea-pig cardiomyocytes by the antipsychotic drug clozapine
1. Clozapine, a commonly used antipsychotic drug, can induce QT prolongation, which may lead to torsades de pointes and sudden death. To investigate the arrhythmogenic side effects of clozapine, we studied the impact of clozapine on human ether-a-go-go-related gene (HERG) channels expressed in Xenop...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751795/ https://ncbi.nlm.nih.gov/pubmed/16633353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706744 |
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