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Intrathecal treatment with σ(1) receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice

1. Although previous reports have suggested that the sigma 1 (σ(1)) receptor may be involved in pain sensation, its specific site of action has not been elucidated. The aim of present study was to determine the role of the spinal σ(1) receptor in formalin-induced pain behavior, spinal cord Fos expre...

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Autori principali: Kim, Hyun-Woo, Kwon, Young-Bae, Roh, Dae-Hyun, Yoon, Seo-Yeon, Han, Ho-Jae, Kim, Kee-Won, Beitz, Alvin J, Lee, Jang-Hern
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751783/
https://ncbi.nlm.nih.gov/pubmed/16682960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706764
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