Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis.

Mutations to the regulatory region of the ahpC gene, resulting in overproduction of alkyl hydroperoxide reductase, were encountered frequently in a large collection of isoniazid (INH)-resistant clinical isolates of Mycobacterium tuberculosis but not in INH-susceptible strains. Overexpression of ahpC...

詳細記述

書誌詳細

出版年:	Infect Immun
主要な著者:	Heym, B, Stavropoulos, E, Honoré, N, Domenech, P, Saint-Joanis, B, Wilson, T M, Collins, D M, Colston, M J, Cole, S T
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1997
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175145/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.4.1395-1401.1997
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