Substrate Selectivity of Epidermal Growth Factor-Receptor Ligand Sheddases and their Regulation by Phorbol Esters and Calcium Influx

Signaling via the epidermal growth factor receptor (EGFR), which has critical roles in development and diseases such as cancer, is regulated by proteolytic shedding of its membrane-tethered ligands. Sheddases for EGFR-ligands are therefore key signaling switches in the EGFR pathway. Here, we determi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Horiuchi, Keisuke, Le Gall, Sylvain, Schulte, Marc, Yamaguchi, Takafumi, Reiss, Karina, Murphy, Gillian, Toyama, Yoshiaki, Hartmann, Dieter, Saftig, Paul, Blobel, Carl P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2007
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751309/
https://ncbi.nlm.nih.gov/pubmed/17079736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-01-0014
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