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Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic β-cells

1. S 21403 (mitiglinide) is a new drug for type 2 diabetes mellitus (T2DM). Its action on insulin release and biosynthesis was investigated in several experimental systems utilizing pancreas from normal and T2DM animals. 2. At high concentrations (10 μM), S 21403, like classical sulphonylurea, induc...

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Detalhes bibliográficos
Main Authors: Kaiser, Nurit, Nesher, Rafael, Oprescu, Andrei, Efendic, Suad, Cerasi, Erol
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751216/
https://ncbi.nlm.nih.gov/pubmed/16158072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706374
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