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Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic β-cells
1. S 21403 (mitiglinide) is a new drug for type 2 diabetes mellitus (T2DM). Its action on insulin release and biosynthesis was investigated in several experimental systems utilizing pancreas from normal and T2DM animals. 2. At high concentrations (10 μM), S 21403, like classical sulphonylurea, induc...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751216/ https://ncbi.nlm.nih.gov/pubmed/16158072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706374 |
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