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Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells

1. Mutations in p53, a tumor suppressor gene, occur in more than half of human cancers. Therefore, we tested the hypothesis that jasmonates (novel anticancer agents) can induce death in mutated p53-expressing cells. 2. Two clones of B-lymphoma cells were studied, one expressing wild-type (wt) p53 an...

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Detalhes bibliográficos
Main Authors: Fingrut, Orit, Reischer, Dorit, Rotem, Ronit, Goldin, Natalia, Altboum, Irit, Zan-Bar, Israel, Flescher, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751213/
https://ncbi.nlm.nih.gov/pubmed/16170329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706394
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