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PI3K/Akt Pathway Activation Attenuates the Cytotoxic Effect of Methyl Jasmonate Toward Sarcoma Cells

Methyl jasmonate (MJ) acts both in vitro and in vivo against various cancer cell lines. Activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway results in decreased susceptibility to cytotoxic agents in many types of cancer cells. We found a strong inverse correlation between the basal le...

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Detalhes bibliográficos
Main Authors: Elia, Uri, Flescher, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570607/
https://ncbi.nlm.nih.gov/pubmed/18953440
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