Production of interleukin-8 (IL-8) by cultured endothelial cells in response to Borrelia burgdorferi occurs independently of secreted [corrected] IL-1 and tumor necrosis factor alpha and is required for subsequent transendothelial migration of neutrophils.

Previous studies have shown that Borrelia burgdorferi, the spirochetal agent of Lyme disease, promotes inflammation by stimulating endothelial cells to upregulate adhesion molecules for leukocytes and to produce a soluble agent that is chemotactic for neutrophils. We determined that interleukin-8 (I...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Burns, M J, Sellati, T J, Teng, E I, Furie, M B
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175120/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9119454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.4.1217-1222.1997
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