Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.

The combined antiviral effects of various 2',3'-dideoxynucleosides and ribavirin on the replication of human immunodeficiency virus type 1 in MT-4 cells have been examined. Ribavirin antagonized the antiviral activity of the pyrimidine 2',3'-dideoxynucleosides (3'-azido-2',3'-dideoxythymidine, 2',3'...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Baba, M, Pauwels, R, Balzarini, J, Herdewijn, P, De Clercq, E, Desmyter, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3435108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.10.1613
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