Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity.

A novel nucleoside analog, 4(5H)-oxo-1-beta-D- ribofuranosylpyrazolo[3,4-d]pyrimidine-3-thiocarboxamide (N10169), was evaluated in cell culture and in animals for antiviral activity against DNA and RNA viruses. The compound was highly active against strains of adeno-, vaccinia, influenza B, paramyxo...

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Bibliografiska uppgifter
Huvudupphovsmän: Smee, D F, McKernan, P A, Nord, L D, Willis, R C, Petrie, C R, Riley, T M, Revankar, G R, Robins, R K, Smith, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC174985/
https://ncbi.nlm.nih.gov/pubmed/3435102
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